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sparsentan will lower the extent or influence of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and reduces efficacy linked to these substrates.Hou et al (2005) studied the autonomic consequences of modafinil in people. They located that modafini
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